Bears vs. Colts NFL Week 3 prediction, odds and best bet: Can either QB find their rhythm?

The Chicago Bears travel to Lucas Oil Stadium for a midwestern showdown with the Indianapolis Colts in what should be an exciting matchup between two young and exciting teams.

Currently, sportsbooks favor the Colts as 1 to 1.5-point favorites at home. With such a tight line, it shows that this game could really go either way, Caesars Sportsbook even has the game line set at PK. Check the latest odds below, but let's get into my prediction right away for who will win.

My Bears vs. Colts prediction for Week 3 Pick: Chicago Bears +1 (-110 at Bet365)

In what should be a fun matchup in the afternoon slate, I expect Chicago to take control of this game defensively to help win the field position battle and eventually take control of this game. While the Colts have the pieces to succeed, they've been too sloppy to feel confident in as they go against one of the better defenses in the league.

If Richardson can play a clean game and show some further development in the short to intermediate game though, that will be a tremendous boost in Indianapolis' favor.

Other lines surrounding this game that stand out include under 22.5 on the Colts total points (-110 on FanDuel Sportsbook ) and D.J. Moore over 60.5 receiving yards (-115 on DraftKings Sportsbook ).

If you need to know more about the various bets you can use at sportsbooks in Ohio, check out our How To Bet reference guide.

NFL Week 3 Bears vs. Colts odds Indianapolis enters Week 3 without a victory after losing to their division rival Houston Texans to open the season, then getting upset by the Malik Willis-led Packers. Still, the team has plenty of splash plays that should help them build up momentum as the season progresses.

The Colts' moneyline odds vary between -110 and -115. While Chicago's has a range of -104 to -110. The point total for this matchup is set at 43.5 with the best odds featured at BetMGM Sportsbook at -110.

Why the Colts could win as the favorite Despite an ugly Week 2 outing, the Indianapolis offense is still one of the more impressive units thanks to their ability to control games on the ground. Shane Steichen is one of the best offensive minds, and the team was able to generate over 7.7 yards per carry against the Packers.

Defensively, the Indianapolis pass rush is very exciting. Gus Bradley has been operating with a blitz-heavy approach, and against a struggling Bears' offensive line, that could be the recipe for success to get Caleb Williams uncomfortable early.

Anthony Richardson will need to play more disciplined, as his four interceptions through the first two weeks have been detrimental to the team's chances of winning games. If he can limit his turnovers and sustain drives, then Indianapolis could earn their first victory of the year.

Why the Bears could win as the underdog It's easier to say that Richardson needs to be more consistent than it is to actually do so when facing off against one of the league's top defensive units. Matt Eberflus (formerly a defensive coordinator of the Colts) has found his groove with this Chicago roster, and has been able to limit opposing offenses as a result.

Offensively, the biggest advantage for Chicago is their weapons room. D.J. Moore and Rome Odunze have a clear leg up on Indianapolis' lacking secondary. If Williams can get comfortable early, then there is potential for a big day through the air.

Similar to Indy, the potential is there for the Bears to take the next step and find their groove. But a lot of that is contingent on the offensive line and play-calling improving to unleash that upside. Week 3 will be a good test for this unit to potentially evolve.