Chicago White Sox at San Diego Padres odds, picks and predictions

The Chicago White Sox (36-117) open a 3-game series on the road against the San Diego Padres (87-66) Friday night. First pitch from Petco Park is at 9:40 p.m. ET. Let's analyze BetMGM Sportsbook's MLB odds around the White Sox vs. Padresodds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Padres won 3-0 last season

The White Sox have only 9 wins since the All-Star break. They have lost 2 in a row after winning 3 straight and are coming off a 4-3 loss at the Los Angeles Angels on Wednesday.

The Padres lead the NL Wild Card race and trail the LA Dodgers by 4 games for the NL West lead. They have won 5 of their last 6 games and are coming off a series-clinching 4-0 win on Wednesday at home over the Houston Astros.

White Sox at Padres projected startersGarrett Crochet vs. RHP Joe Musgrove

Crochet (6-12, 3.78 ERA) makes his 31st start. He has a 1.09 WHIP, 2.1 BB/9 and 12.7 K/9 in 138 IP.

Last start: Loss, 4 in 2-0 home loss to Oakland A's last Friday Has not had a win since June 7 Has not pitched more than 4 IP in last 9 starts Has pitched 1 scoreless inning in his career vs. Padres Musgrove (6-5, 4.23 ERA) makes his 18th start. He has a 1.23 WHIP, 2.3 BB/9 and 8.9 K/9 in 87 1/3 IP.

Last start: Win, 6 in 8-0 road win over San Francisco Giants on Saturday Is 3-1 with 2.37 ERA in 7 starts since returning from injured list Has 7 1/3 scoreless innings in 3 career games (1 start) vs. ChicagoWho's going yard? Here's a breakdown of today's best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

White Sox at Padres odds Provided by BetMGM Sportsbook ; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of MLB odds . Lines last updated at 8:46 a.m. ET.

Moneyline (ML): White Sox +200 (bet $100 to win $200) | Padres -250 (bet $250 to win $100)Run line (RL)/Against the spread (ATS): White Sox +1.5 (-110) | Padres -1.5 (-110)Over/Under (O/U): 7 (O: -110 | U: -110) White Sox at Padres picks and predictions Padres 4, White Sox 2

At this point, you should probably never bet on the White Sox on the moneyline. They have the fewest wins in all of baseball. They have only 9 wins since the All-Star Game.

The Padres have won 10 of their last 15, but betting them at -250 isn't worth the action.

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Run line/Against the spread Twelve of Chicago's last 13 losses have been by at least 2 runs while 10 of the Padres' last 13 wins have been by 2 or more runs.

The White Sox are 31-44 ATS on the road.

BET PADRES -1.5 (-110).

Over/Under Six of the Padres' last 7 games have not reached 8 total runs while 4 of the last 6 for Chicago have not either. Five of their last 8 losses have not either.

Five of Musgrove's 7 starts since returning from IL had not reached 8 total runs.

BET UNDER 7 (-110).

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